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Chronic Osteomyelitis, options?

22 11:12:22

Question
Hi, been reading your advice for various rabbit owners and was hoping you could send some my way!
I live in the Uk and am seen by my local vet who has learnt with my bunny combined with input from "specialist" vet in Andover. Both of them are fantastic,but always seem to agree on his care. I work as a childrens' nurse and value the second opinion of another professional!
Dobby, is 3yrs and has had numerous medical problems. His first abscess was at 6 months, this was treated and there seemed to be no further problems. However at 18months he then went into gut stasis and was diagnosed with an old pelvis fracture and osteomylitis of the skull. We started metacam (anti-inflam) and septrin on daily basis. Since then gut stasis has flared up on 6monthly basis and we manage this with critical care, sub-cut fluids, prepulsid, ranitidine, simethiscone, increased metacam. (He's also developed hepatic lipidosis and so requires milk thistle tincture to help liver function).
But the point of this question relates to the past 6 months were Dobby has had recurrent abscesses along the lower left jaw. These have been removed and gentamicin impregnated beads (from C+S) have been implanted and switched antibiotic to baytril orally. This seemed to be working, until a locum vet removed and did not replace bead!On x-ray, the specialist described the osteomyelitis as stage 5 out of 5, throughout the skull and therefore not appropriate for removal of sections of the mandible. I just wondered if there were any potential treatments available, please don't say bicillin, as it is still illegal to import or use over here.
Any help greatly appreciated.
Laura and Dobby

Answer
Dear Laura,

I've not had good luck with bead implantation.  And I know that bicillin isn't available in the UK (we still can't figure that one out!), but you *can* get Penicillin-G Procaine, which is one of the two ingredients of bicillin.  (If your vet can also get Benzathine, another form of Penicillin, and administer them together, then that's basically bicillin.)

You might be able to find some helpful tips here:

www.bio.miami.edu/hare/jawabscess.html

and particularly from the article linked there by Tyrrell, et al.  Please feel free to share any of the information with your vets, though it does sound as if they are on top of things.

I hope this will help!

Dana