amitraz dips - safety

Question
I am 8 weeks pregnant.  My dog has had a treatment of the amitraz dip and has come home.  He usually goes to the vet early in t he morning and does not come home until he is dry at the end of the day. What are my limitations with him?  Is it safe to be around him?  Is is safe to pet
him?

Answer
Reproductive Effects: Doses of 200 mg/kg/day of amitraz for ten weeks decreased fertility in male and female rats. Female mice treated orally for 5 days with 50 mg/kg/day of amitraz and then mated showed a slight increase in loss of fetuses and a decrease in the number of living offspring. When male mice were given 50 mg/kg/day of amitraz orally for 5 days and then mated, the resulting embryos were significantly less likely to grow in the mother's uterus. Female mice who received 400 mg/kg/day of amitraz in their diet for up to 33 weeks, showed a significant increase in the time they were sexually receptive (227). The highest dose of amitraz which has no observable effect on the death of unborn rats (fetotoxic NOEL) is 3 mg/kg/day. The highest dose of amitraz that does not cause an observable effect in the death of rat embryos (Embryotoxic NOEL) is 5 mg/kg/day (228). Rats who received 12 mg/kg/day of amitraz from day one of pregnancy until the young were weaned at 21 days old had a reduced number of young born and alive at day four (227). Rabbits who received 25 mg/kg/day of amitraz from days 6 to 18 of pregnancy had fewer and smaller litters (223). Although there have been reproductive effects observed in laboratory animals at some dose levels, likely human exposures are very much less than those which produced effects. These effects are unlikely in humans under normal circumstances.


I would advise you not to be in contact with the dog for 3 days after the mitaban dips, when the copncentration is the highest on the skin.