Great dane gestation

Question
At what point will we see a difference if our great Dane is pregnant?

Answer
Hi Beatrice,
Four to six weeks should show a redness to her nipples and also a slight puffiness.  Her vulva should remain swollen as if she was still in season.  She should also start to gain a bit  of weight from this point on.  If she has a small litter inside of her, it will be harder to see any movement.
Nancy