Strange liquid

Question
Species:Leopard Gecko
Habitat:26 Gal. tank
Size: Large
Substrate: Calcuim sand
Humidity- N/A
Vet History- Has never been to a vet
Food offered- pinkies, mealworms, wax worms, crickets.
Last time it eat was 05/04
Defecated- n/a
Captive bred- yes
Shed- today 05/04

I have two leopard Gecko's, One is a patternless male blizzard who is about 9 and the other is a normal female about 2 or three.
Not too long ago I found what looked like a weird egg in their tank((the tank is shared between the two). I looked at the egg thing with a light to see if I could see anything and I could so I broke it open and it was just a nasty cloudy liquid that smelled really bad.
That was the last time something like that happened. But now she's have the same cloudy liquid come out when she goes to the bathroom. Also her tail is starting to get skinny and I think that's why. I can't find anything that sounds like what she has.

Answer
It sounds as if she may be egg bound and had more eggs that did not pass. When this happens they usually stop eating when it gets serious, and infection sets in after a time when the eggs don't pass and finally rupture. That is what is probably causing her loss of fat stores in the tail. I would guess she is probably less active, may be lethargic and disinterested in eating due to egg binding and infection.

You need to get her to a vet ASAP for an exam to check for egg binding and to treat her with systemic antibiotics. The liquid you observed could be many things...but none of them good, as a Leopard Gecko should not be passing ANY liquid substances. Liquid usually means kidney failure or a serious infection. This could be the fluid from retained eggs that have finally ruptured, in which case it is a very serious situation, as too much time has passed and the contents of any retained eggs would be well spoiled. A biohazard to her in fact. Many geckos, iguanas, and beardies, etc. die from these complications due to sepsis.

We have a female Leo that is over 10 years old, so make sure your Leo has a long and healthy life, by taking her to a reptile vet immediately.  

http://drgecko.com

PS-get rid of any strictly calcium based sands such as calci-sand. Vitasand is a little more safe, but I would urge you to stick to fine grade playbox sand from the hardware store if you want to use a natural substrate. Calcium based sands such as calci-sand are an impaction hazard due to the clumping of calcium, and they usually contain large sharp pieces of shellfish that should not be ingested.