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Ponazuril dilution

22 11:04:47

Question
Hi Dana,
Could you please email the dilution for the equine ponazuril.  My vet just started using it but we would like to do it at home since we do rescue/fostering/adoptions.
Thanks for your help,
Sharon

Answer
Hi, Sharon

Here's the dilution my husband mixes up in the lab.  Says Kevin:

I dilute it to 5% w/vol, or approximately 50 mg/mL in distilled water (i.e.
I add 2 mL water to every g paste).  This still is fairly thick, yet dilute
enough to be shaken into a uniform suspension and be drawn into a syringe.
I have the benefit of an analytical balance at work for weighing out small
amounts, but you probably can get by with estimating volumes, i.e. 1 part
paste to two parts water.  (I think the dosage is fairly flooby, so don't
angst over whether your diluted suspension is *exactly* 50mg/mL.)

Hope that helps.

Dana