My female boxer dog age 2 years.

Question
I have two boxer dogs a male of 4 and a female of 2 who was spaded after her first season. My female boxers sometimes leaks urine and wets her bedding. I have researched this on the Internet and this could be to do with her spading.I had no major concerns as this seemed to have stopped until recently i noticed her bedding being wet again and a small urine patch on my rug where she had been laying. I am not sure if it is related or a total separate thing but since yesterday my female boxer has refused to eat,i have tryed her favorite things like chicken etc and still she will not eat, she doesn,t seem herself and is vomiting a white flem. I presume she is hungry as i gave her a dog biscuit and she would not eat it but became protective of it when my male boxer approached her she really attacked him i have never seen her go for him before they are usually best friends. She doesn't seem very tolerable of him at all and is growling when he comes near her. Ten minutes later she will be cuddling into him.This is unusual behavior from her.  

Answer
Let me correct your terminology first... it is not "spaded" it is "spayed."

Apparently she is sick...something is wrong.

When she cannot hold her bladder, and leaking urine while laying, not eating, and mood swings....chances are she is quite ill.

It could possibly be a bladder/urinary infection causing her not to be able to hold her bladder contents and it leaking as well, loss of appetite, and irritability from not felling well.

Get her to a vet ASAP. Urinary infections are very serious and left untreated, can spread to kidneys and cause kidney failure, as well as infection in her blood stream spreading throughout her body.

She needs tests, proper diagnosis, and medication.