Manganese And Prostate Health

Manganese is an essential trace mineral. It is essential to the health and functioning of the human body and human mind in several ways. The adult human body contains about 10 to 20 milligrams of manganese. Manganese is stored half in the bones and the remainder in the liver, pancreas, pituitary gland, and kidneys. Manganese is called the "brain mineral," because it is important in the utilization of all mental facilities/functions. It supports memory and emotional stability, as well as the nerves themselves. Thiamin, or Vitamin B1, cannot be metabolized without the presence of this essential mineral.  Reproductive HealthManganese serves the reproductive system, enjoying an important role in the production of sex hormones and sperm. As a catalyst in the synthesis of fatty acids and cholesterol, manganese also participates in the production of sex hormones, thus helping to maintain reproductive health.  Manganese has a positive effect on the male reproductive system. Studies show that Manganese nutritionally supports the following functions: '         It increases energy levels of the libido and the brain's ability to receive and send messages. 1'         It helps the reproductive organs to work properly because of its effect on tissues and nerves.2 '         Production of sex hormones is aided by manganese. '         Manganese is beneficial to sperm motility. 3'         Maintains reproductive health. 4 For men, manganese deficiency may cause sterility, low sex drive, and low sperm count. Low levels of manganese in the body may also inhibit the synthesis of sex hormones and can contribute to infertility.  Other Functions'         The skeletal system needs manganese for the building of strong and healthy bones. Manganese makes up part of a molecule known as mucopolysaccharides, which are used to form collagen. This mesh of collagen is the framework on which calcium, magnesium, and other bone building minerals are deposited. '         Manganese activates the enzymes known as glycolsyltranserferases and xylosyltransferases, which are important in the formation of bone.'         Manganese strengthens tendons, tissues, ligaments, and linings in and outside of organs. '         Manganese also serves the nervous system and brain, supporting good muscular reflexes. '         It promotes the natural immune functions, and aids in oxygen transfer from lungs to cells.'         Manganese works in the digestive system acting as a cofactor in many of the enzymes responsible for releasing the energy in food, making it accessible to both body and mind for fuel. '         Manganese is a part of the enzyme, superoxide dismutase (MnSOD), a powerful antioxidant. Antioxidants can neutralize free radicals and may reduce or even help prevent some of the damage they cause. Preliminary experimental studies show MnSOD may reduce the risk of prostate cancer in certain men. The Health and Nutrition Examination Survey estimate that as many as 30% of Americans do not get the recommended daily amounts of manganese in their diet. This may be due to the fact that whole grains are a major source of dietary manganese, and many Americans consume refined grains more often than whole grains. The milling of grains removes 73% of manganese.  Natural Food SourcesTea, whole grains, raw nuts, and green leafy veggies, avocados, carrots, pineapples, eggs are rich sources of manganese, with other fruits and vegetables containing moderate amounts. Maple syrup may help to support reproductive health and provides special benefits for men due to its zinc and manganese content.  Clinical studies have supported that Manganese is necessary healthy prostate and sexual functioning, protein and fat metabolism, healthy nerves, healthy immune system, blood sugar regulation, as well as bone and cartilage growth, muscle coordination and proper blood clotting.  References:1.       Takeda A, Sotogaku N, Oku N. Manganese influences the levels of neurotransmitters in synapses in rat brain. Neuroscience. 2002;114(3):669-74.2.       Finley JW, Johnson PE, Johnson LK. Sex affects manganese absorption and retention by humans from a diet adequate in manganese. Am J Clin Nutr. 1994;60(6):949-955. (PubMed). 3.       Magnus O, Brekke I, Abyholm T, Purvis K, Effects of manganese and other divalent cations on progressive motility of human sperm. Arch Androl. 1990;24(2):159-66. Department of Gynecology and Obstetrics, National Hospital, Oslo, Norway.

4. Lee B, Pine M, Johnson L, Rettori V, Hiney JK, Dees WL. Manganese acts centrally to activate reproductive hormone secretion and pubertal development in male rats. Reprod. Toxicol. (2006) 22:580585.