Cerebellar degeneration in cats is a brain disease that affects a specific area of the brain known as the cerebellum. In cerebellar degeneration, the cells within the cerebellum die, causing neurological symptoms.
Symptoms of cerebellar degeneration in cats include:
Infection with feline panleukopenia virus either in utero or as a neonate may cause cerebellar degeneration. A genetic predisposition for the condition is seen in dogs and may also be possible in cats.
MRI (magnetic resonance imaging) may reveal a smaller than normal cerebellum. Cerebrospinal fluid analysis may be normal or abnormal depending on the individual cause. Biopsy of the cerebellum is the definitive means of diagnosis.
Routine blood and urine testing may be necessary to rule out other disease conditions which may appear similar.
There is no curative treatment, but medications such as amantidine, buspirone, co-enzyme Q10 and acetyl-l-carnitine have shown some promise.
Because of the lack of coordination associated with this condition, restrict the cat’s activity to safe areas of the household where injury cannot occur. Avoid stairs, sharp objects, swimming pools, and other dangers.
Another effect of incoordination in the cat may present as trouble eating. The cat may require physical aid in eating, though it can continue to eat a normal diet. Nursing care to keep the cat free of urine and feces may also be necessary.
To protect your cat and potential offspring from brain disease, avoid vaccinating pregnant queens with modified live virus vaccines, particularly the feline panleukopenia vaccine.
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